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Edgetic perturbation signatures represent known and novel cancer biomarkers
Isoform switching is a recently characterized hallmark of cancer, and often translates to the loss or gain of domains mediating protein interactions and thus, the re-wiring of the interactome. Recent computational tools leverage domain-domain interaction data to resolve the condition-specific intera...
Autores principales: | Kataka, Evans, Zaucha, Jan, Frishman, Goar, Ruepp, Andreas, Frishman, Dmitrij |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062722/ https://www.ncbi.nlm.nih.gov/pubmed/32152446 http://dx.doi.org/10.1038/s41598-020-61422-3 |
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