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Multiplexed CRISPR technologies for gene editing and transcriptional regulation

Multiplexed CRISPR technologies, in which numerous gRNAs or Cas enzymes are expressed at once, have facilitated powerful biological engineering applications, vastly enhancing the scope and efficiencies of genetic editing and transcriptional regulation. In this review, we discuss multiplexed CRISPR t...

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Detalles Bibliográficos
Autores principales: McCarty, Nicholas S., Graham, Alicia E., Studená, Lucie, Ledesma-Amaro, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062760/
https://www.ncbi.nlm.nih.gov/pubmed/32152313
http://dx.doi.org/10.1038/s41467-020-15053-x