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Multiplexed CRISPR technologies for gene editing and transcriptional regulation
Multiplexed CRISPR technologies, in which numerous gRNAs or Cas enzymes are expressed at once, have facilitated powerful biological engineering applications, vastly enhancing the scope and efficiencies of genetic editing and transcriptional regulation. In this review, we discuss multiplexed CRISPR t...
Autores principales: | McCarty, Nicholas S., Graham, Alicia E., Studená, Lucie, Ledesma-Amaro, Rodrigo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062760/ https://www.ncbi.nlm.nih.gov/pubmed/32152313 http://dx.doi.org/10.1038/s41467-020-15053-x |
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