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Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin

Endophilins-A are conserved endocytic adaptors with membrane curvature-sensing and -inducing properties. We show here that, independently of their role in endocytosis, endophilin-A1 and endophilin-A2 regulate exocytosis of neurosecretory vesicles. The number and distribution of neurosecretory vesicl...

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Detalles Bibliográficos
Autores principales: Gowrisankaran, Sindhuja, Houy, Sébastien, del Castillo, Johanna G. Peña, Steubler, Vicky, Gelker, Monika, Kroll, Jana, Pinheiro, Paulo S., Schwitters, Dirk, Halbsgut, Nils, Pechstein, Arndt, van Weering, Jan R. T., Maritzen, Tanja, Haucke, Volker, Raimundo, Nuno, Sørensen, Jakob B., Milosevic, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062783/
https://www.ncbi.nlm.nih.gov/pubmed/32152276
http://dx.doi.org/10.1038/s41467-020-14993-8