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Pancreatic islets seeded in a novel bioscaffold forms an organoid to rescue insulin production and reverse hyperglycemia in models of type 1 diabetes

Therapeutic approaches to combat type 1 diabetes (T1D) include donor pancreas transplantation, exogenous insulin administration and immunosuppressive therapies. However, these clinical applications are limited due to insufficient tissue compatible donors, side effects of exogenous insulin administra...

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Detalles Bibliográficos
Autores principales: Elizondo, Diana M., Brandy, Nailah Z. D., da Silva, Ricardo L. L., de Moura, Tatiana R., Ali, Jamel, Yang, Dazhi, Lipscomb, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062832/
https://www.ncbi.nlm.nih.gov/pubmed/32152396
http://dx.doi.org/10.1038/s41598-020-60947-x