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Angiotensin II represses Npr1 expression and receptor function by recruitment of transcription factors CREB and HSF-4a and activation of HDACs

The two vasoactive hormones, angiotensin II (ANG II; vasoconstrictive) and atrial natriuretic peptide (ANP; vasodilatory) antagonize the biological actions of each other. ANP acting through natriuretic peptide receptor-A (NPRA) lowers blood pressure and blood volume. We tested hypothesis that ANG II...

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Detalles Bibliográficos
Autores principales: Arise, Kiran K., Kumar, Prerna, Garg, Renu, Samivel, Ramachandran, Zhao, Hanqing, Pandya, Krishna, Nguyen, Christian, Lindsey, Sarah, Pandey, Kailash N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062852/
https://www.ncbi.nlm.nih.gov/pubmed/32152395
http://dx.doi.org/10.1038/s41598-020-61041-y