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Angiotensin II represses Npr1 expression and receptor function by recruitment of transcription factors CREB and HSF-4a and activation of HDACs
The two vasoactive hormones, angiotensin II (ANG II; vasoconstrictive) and atrial natriuretic peptide (ANP; vasodilatory) antagonize the biological actions of each other. ANP acting through natriuretic peptide receptor-A (NPRA) lowers blood pressure and blood volume. We tested hypothesis that ANG II...
Autores principales: | Arise, Kiran K., Kumar, Prerna, Garg, Renu, Samivel, Ramachandran, Zhao, Hanqing, Pandya, Krishna, Nguyen, Christian, Lindsey, Sarah, Pandey, Kailash N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062852/ https://www.ncbi.nlm.nih.gov/pubmed/32152395 http://dx.doi.org/10.1038/s41598-020-61041-y |
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