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Targeting the Oncogenic TBX2 Transcription Factor With Chromomycins

The TBX2 transcription factor plays critical roles during embryonic development and it is overexpressed in several cancers, where it contributes to key oncogenic processes including the promotion of proliferation and bypass of senescence. Importantly, based on compelling biological evidences, TBX2 h...

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Detalles Bibliográficos
Autores principales: Sahm, Bianca Del B., Peres, Jade, Rezende-Teixeira, Paula, Santos, Evelyne A., Branco, Paola C., Bauermeister, Anelize, Kimani, Serah, Moreira, Eduarda A., Bisi-Alves, Renata, Bellis, Claire, Mlaza, Mihlali, Jimenez, Paula C., Lopes, Norberto P., Machado-Santelli, Glaucia M., Prince, Sharon, Costa-Lotufo, Leticia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062867/
https://www.ncbi.nlm.nih.gov/pubmed/32195221
http://dx.doi.org/10.3389/fchem.2020.00110