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Targeting the Oncogenic TBX2 Transcription Factor With Chromomycins
The TBX2 transcription factor plays critical roles during embryonic development and it is overexpressed in several cancers, where it contributes to key oncogenic processes including the promotion of proliferation and bypass of senescence. Importantly, based on compelling biological evidences, TBX2 h...
Autores principales: | Sahm, Bianca Del B., Peres, Jade, Rezende-Teixeira, Paula, Santos, Evelyne A., Branco, Paola C., Bauermeister, Anelize, Kimani, Serah, Moreira, Eduarda A., Bisi-Alves, Renata, Bellis, Claire, Mlaza, Mihlali, Jimenez, Paula C., Lopes, Norberto P., Machado-Santelli, Glaucia M., Prince, Sharon, Costa-Lotufo, Leticia V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062867/ https://www.ncbi.nlm.nih.gov/pubmed/32195221 http://dx.doi.org/10.3389/fchem.2020.00110 |
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