MCC950, a Selective Inhibitor of NLRP3 Inflammasome, Reduces the Inflammatory Response and Improves Neurological Outcomes in Mice Model of Spinal Cord Injury

Spinal cord injury (SCI) is a serious condition that affects bodily function; however, there is no effective therapy in clinical practice. MCC950, a selective NOD-like receptor protein-3 (NLRP3) inflammasome inhibitor, has been reported to alleviate canonical and non-canonical NLRP3 inflammasome act...

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Detalles Bibliográficos
Autores principales: Jiao, Jianhang, Zhao, Guanjie, Wang, Yang, Ren, Pengfei, Wu, Minfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062868/
https://www.ncbi.nlm.nih.gov/pubmed/32195267
http://dx.doi.org/10.3389/fmolb.2020.00037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062868/
https://www.ncbi.nlm.nih.gov/pubmed/32195267
http://dx.doi.org/10.3389/fmolb.2020.00037

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