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Neuroprotective Effects of Necrostatin-1 Against Oxidative Stress–Induced Cell Damage: an Involvement of Cathepsin D Inhibition

Necroptosis, a recently discovered form of non-apoptotic programmed cell death, can be implicated in many pathological conditions including neuronal cell death. Moreover, an inhibition of this process by necrostatin-1 (Nec-1) has been shown to be neuroprotective in in vitro and in vivo models of cer...

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Detalles Bibliográficos
Autores principales: Jantas, Danuta, Chwastek, Jakub, Grygier, Beata, Lasoń, Władysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062871/
https://www.ncbi.nlm.nih.gov/pubmed/31960265
http://dx.doi.org/10.1007/s12640-020-00164-6