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UVB-dependent inhibition of lipin-1 protects against proinflammatory responses in human keratinocytes

Lipin-1 is an Mg(2+)-dependent phosphatidate phosphatase (PAP1) that catalyzes a critical step in the synthesis of glycerophospholipids and is also a cotranscriptional regulator. The role of lipin-1 in the regulation of inflammatory responses has been extensively studied in various cell types but no...

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Detalles Bibliográficos
Autores principales: Chae, Minjung, Son, Eui Dong, Bae, Il-Hong, Cho, Eun-Gyung, Kim, Hyoung-June, Jung, Ji-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062881/
https://www.ncbi.nlm.nih.gov/pubmed/32080341
http://dx.doi.org/10.1038/s12276-020-0388-y