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Minimal barriers to invasion during human colorectal tumor growth

Intra-tumoral heterogeneity (ITH) could represent clonal evolution where subclones with greater fitness confer more malignant phenotypes and invasion constitutes an evolutionary bottleneck. Alternatively, ITH could represent branching evolution with invasion of multiple subclones. The two models res...

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Detalles Bibliográficos
Autores principales: Ryser, Marc D., Mallo, Diego, Hall, Allison, Hardman, Timothy, King, Lorraine M., Tatishchev, Sergei, Sorribes, Inmaculada C., Maley, Carlo C., Marks, Jeffrey R., Hwang, E. Shelley, Shibata, Darryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062901/
https://www.ncbi.nlm.nih.gov/pubmed/32152322
http://dx.doi.org/10.1038/s41467-020-14908-7