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TIGIT limits immune pathology during viral infections

Co-inhibitory pathways have a fundamental function in regulating T cell responses and control the balance between promoting efficient effector functions and restricting immune pathology. The TIGIT pathway has been implicated in promoting T cell dysfunction in chronic viral infection. Importantly, TI...

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Detalles Bibliográficos
Autores principales: Schorer, Michelle, Rakebrandt, Nikolas, Lambert, Katharina, Hunziker, Annika, Pallmer, Katharina, Oxenius, Annette, Kipar, Anja, Stertz, Silke, Joller, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062903/
https://www.ncbi.nlm.nih.gov/pubmed/32152316
http://dx.doi.org/10.1038/s41467-020-15025-1