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TIGIT limits immune pathology during viral infections
Co-inhibitory pathways have a fundamental function in regulating T cell responses and control the balance between promoting efficient effector functions and restricting immune pathology. The TIGIT pathway has been implicated in promoting T cell dysfunction in chronic viral infection. Importantly, TI...
Autores principales: | Schorer, Michelle, Rakebrandt, Nikolas, Lambert, Katharina, Hunziker, Annika, Pallmer, Katharina, Oxenius, Annette, Kipar, Anja, Stertz, Silke, Joller, Nicole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062903/ https://www.ncbi.nlm.nih.gov/pubmed/32152316 http://dx.doi.org/10.1038/s41467-020-15025-1 |
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