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Mdm2-P53 Interaction Inhibitor with Cisplatin Enhances Apoptosis in Colon and Prostate Cancer Cells In-Vitro

OBJECTIVE: To study the effect of RITA (MDM2-p53 interaction inhibitor) and its action along with genotoxic drug cisplatin was evaluated on COLO-205 colon cancer and PC-3 prostate cancer cells. METHOD: Various in-vitro parameters to determine cytotoxic and apoptotic potential of RITA with genotoxic...

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Detalles Bibliográficos
Autores principales: Gupta, Amit, Behl, Tapan, Heer, Hem Raj, Deshmukh, Rahul, Sharma, Pyare Lal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062994/
https://www.ncbi.nlm.nih.gov/pubmed/31759358
http://dx.doi.org/10.31557/APJCP.2019.20.11.3341