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The Role of the LY294002 - A Non-Selective Inhibitor of Phosphatidylinositol 3-Kinase (PI3K) Pathway- in Cell Survival and Proliferation in Cell Line SCC-25

The activation of PI3K further activates subsequent regulatory pathways, which are activated via AKT phosphorylation. AKT is closely related to the Bcl-2 family, a protein known to be involved in cell survival. AKT also has a relationship with inflammatory and glycolytic mediators. The present work...

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Detalles Bibliográficos
Autores principales: Duarte, Andressa, Giórgia Gobbi, Giórgia Gobbi, Soave, Danilo Figueiredo, Oliveira Costa, João Paulo, Silva, Alfredo Ribeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063005/
https://www.ncbi.nlm.nih.gov/pubmed/31759362
http://dx.doi.org/10.31557/APJCP.2019.20.11.3377