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Association between C1236T Genetic Variant of ABCB1 Gene and Molecular Response to Imatinib in Indonesian Chronic Myeloid Patients

OBJECTIVE: Imatinib is the first-line drug used for the treatment of chronic myeloid leukemia (CML) patients due to high molecular response and overall survival rate. However, some patients develop resistance to imatinib even after attaining a response. Mutation in ABCB1 efflux transporters is one o...

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Detalles Bibliográficos
Autores principales: Rinaldi, Ikhwan, Nova, Riki, Widyastuti, Reni, Priambodo, Rizky, Instiaty, Instiaty, Louisa, Melva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063013/
https://www.ncbi.nlm.nih.gov/pubmed/31759356
http://dx.doi.org/10.31557/APJCP.2019.20.11.3331