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Robust induction of neural crest cells to derive peripheral sensory neurons from human induced pluripotent stem cells
Because intractable itch reduces quality of life, understanding the fundamental mechanisms of itch is required to develop antipruritic treatments. Itch is mediated by peripheral sensory neurons, which originate from the neural crest (NC) during development. Itch-associated signaling molecules have b...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063040/ https://www.ncbi.nlm.nih.gov/pubmed/32152328 http://dx.doi.org/10.1038/s41598-020-60036-z |