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Robust induction of neural crest cells to derive peripheral sensory neurons from human induced pluripotent stem cells

Because intractable itch reduces quality of life, understanding the fundamental mechanisms of itch is required to develop antipruritic treatments. Itch is mediated by peripheral sensory neurons, which originate from the neural crest (NC) during development. Itch-associated signaling molecules have b...

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Detalles Bibliográficos
Autores principales: Umehara, Yoshie, Toyama, Sumika, Tominaga, Mitsutoshi, Matsuda, Hironori, Takahashi, Nobuaki, Kamata, Yayoi, Niyonsaba, François, Ogawa, Hideoki, Takamori, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063040/
https://www.ncbi.nlm.nih.gov/pubmed/32152328
http://dx.doi.org/10.1038/s41598-020-60036-z