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Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival

Regulation of mitosis secures cellular integrity and its failure critically contributes to the development, maintenance, and treatment resistance of cancer. In yeast, the dual phosphatase Cdc14 controls mitotic progression by antagonizing Cdk1-mediated protein phosphorylation. By contrast, specific...

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Detalles Bibliográficos
Autores principales: Dietachmayr, Michael, Rathakrishnan, Abirami, Karpiuk, Oleksandra, von Zweydorf, Felix, Engleitner, Thomas, Fernández-Sáiz, Vanesa, Schenk, Petra, Ueffing, Marius, Rad, Roland, Eilers, Martin, Gloeckner, Christian Johannes, Clemm von Hohenberg, Katharina, Bassermann, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063047/
https://www.ncbi.nlm.nih.gov/pubmed/32152317
http://dx.doi.org/10.1038/s41467-020-15059-5