Mitochondria as target to inhibit proliferation and induce apoptosis of cancer cells: the effects of doxycycline and gemcitabine

Doxycycline has anti-tumour effects in a range of tumour systems. The aims of this study were to define the role mitochondria play in this process and examine the potential of doxycycline in combination with gemcitabine. We studied the adenocarcinoma cell line A549, its mitochondrial DNA-less deriva...

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Detalles Bibliográficos
Autores principales: Dijk, Sas N., Protasoni, Margherita, Elpidorou, Marilena, Kroon, Albert M., Taanman, Jan-Willem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063048/
https://www.ncbi.nlm.nih.gov/pubmed/32152409
http://dx.doi.org/10.1038/s41598-020-61381-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063048/
https://www.ncbi.nlm.nih.gov/pubmed/32152409
http://dx.doi.org/10.1038/s41598-020-61381-9

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