Modulation of the Endothelin System in Colorectal Cancer Liver Metastasis: Influence of Epigenetic Mechanisms?

Targeting of endothelin system genes is a promising strategy in cancer therapy. The modulation of these genes was explored in a model of colorectal cancer (CRC) liver metastasis and in a panel of CRC tumor cell lines that were exposed to the demethylating agent decitabine. The CC531 rat model mimick...

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Detalles Bibliográficos
Autores principales: Mahdi, Mohamed R., Georges, Rania B., Ali, Doaa M., Bedeer, Raouf F., Eltahry, Huda M., Gabr, Abd-El Hakiem Z., Berger, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063057/
https://www.ncbi.nlm.nih.gov/pubmed/32194414
http://dx.doi.org/10.3389/fphar.2020.00180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063057/
https://www.ncbi.nlm.nih.gov/pubmed/32194414
http://dx.doi.org/10.3389/fphar.2020.00180

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