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Modeling Oncolytic Viral Therapy, Immune Checkpoint Inhibition, and the Complex Dynamics of Innate and Adaptive Immunity in Glioblastoma Treatment

Oncolytic viruses are of growing interest to cancer researchers and clinicians, due to their selectivity for tumor cells over healthy cells and their immunostimulatory properties. The immune response to an oncolytic virus plays a critical role in treatment efficacy. However, uncertainty remains rega...

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Detalles Bibliográficos
Autores principales: Storey, Kathleen M., Lawler, Sean E., Jackson, Trachette L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063118/
https://www.ncbi.nlm.nih.gov/pubmed/32194436
http://dx.doi.org/10.3389/fphys.2020.00151