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Interaction of oxidative stress and neurotrauma in ALDH2(−/−) mice causes significant and persistent behavioral and pro-inflammatory effects in a tractable model of mild traumatic brain injury

Oxidative stress induced by lipid peroxidation products (LPP) accompanies aging and has been hypothesized to exacerbate the secondary cascade in traumatic brain injury (TBI). Increased oxidative stress is a contributor to loss of neural reserve that defines the ability to maintain healthy cognitive...

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Detalles Bibliográficos
Autores principales: Knopp, Rachel C., Lee, Sue H., Hollas, Michael, Nepomuceno, Emily, Gonzalez, David, Tam, Kevin, Aamir, Daniyal, Wang, Yueting, Pierce, Emily, BenAissa, Manel, Thatcher, Gregory R.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063127/
https://www.ncbi.nlm.nih.gov/pubmed/32155582
http://dx.doi.org/10.1016/j.redox.2020.101486