CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms

Mice overexpressing the nuclear form of CREBH mainly in the liver (CREBH-Tg) showed suppression of high-fat high-sucrose (HFHS) diet-induced obesity accompanied by an increase in plasma fibroblast growth factor 21 (FGF21) levels. CREBH overexpression induced browning in inguinal white adipose tissue...

Descripción completa

Detalles Bibliográficos
Autores principales: Satoh, Aoi, Han, Song-iee, Araki, Masaya, Nakagawa, Yoshimi, Ohno, Hiroshi, Mizunoe, Yuhei, Kumagai, Kae, Murayama, Yuki, Osaki, Yoshinori, Iwasaki, Hitoshi, Sekiya, Motohiro, Konishi, Morichika, Itoh, Nobuyuki, Matsuzaka, Takashi, Sone, Hirohito, Shimano, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063134/
https://www.ncbi.nlm.nih.gov/pubmed/32151974
http://dx.doi.org/10.1016/j.isci.2020.100930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063134/
https://www.ncbi.nlm.nih.gov/pubmed/32151974
http://dx.doi.org/10.1016/j.isci.2020.100930

Ejemplares similares