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RUNX3 Inhibits the Invasion and Metastasis of Human Colon Cancer HT-29 Cells by Upregulating MMP-2/9

OBJECTIVE: To investigate the effect of Runt-associated transcription factor 3 (RUNX3) on the invasion and metastasis of human colon cancer HT-29 cells and to preliminarily explore the mechanism of its anticancer effect. METHODS: The RUNX3 plasmid vector was transfected into human colon cancer HT-29...

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Detalles Bibliográficos
Autores principales: Xue, Jun, Wu, Xueliang, Qu, Ming, Guo, Fei, Han, Lei, Sun, Guangyuan, Yuan, Zelong, Fan, Shuang, Li, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063181/
https://www.ncbi.nlm.nih.gov/pubmed/32184893
http://dx.doi.org/10.1155/2020/5978131