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Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy

PURPOSE: The efficacy of valproic acid (VPA) varies widely in clinical treatment of epileptic patients. Our study is aimed at exploring a potential association between polymorphisms of SCN1A, SCN2A, and UGT2B7 genetic factors and VPA responses. METHODS: In this observational study, a total of 114 ep...

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Detalles Bibliográficos
Autores principales: Lu, Yuan, Su, Quanping, Li, Ming, Dayimu, Alimu, Dai, Xiaoyu, Wang, Zhiheng, Che, Fengyuan, Xue, Fuzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063186/
https://www.ncbi.nlm.nih.gov/pubmed/32185219
http://dx.doi.org/10.1155/2020/8096235