A Cell- and Tissue-Specific Weakness of the Protein Homeostasis System Underlies Brain Vulnerability to Protein Aggregation

The phenomenon of protein misfolding and aggregation is associated with a wide range of neurodegenerative conditions that cause progressive loss of function in specific regions of the human brain. To understand the causes of the selective cell and tissue vulnerability to the formation of these depos...

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Detalles Bibliográficos
Autores principales: Kundra, Rishika, Dobson, Christopher M., Vendruscolo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063235/
https://www.ncbi.nlm.nih.gov/pubmed/32146327
http://dx.doi.org/10.1016/j.isci.2020.100934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063235/
https://www.ncbi.nlm.nih.gov/pubmed/32146327
http://dx.doi.org/10.1016/j.isci.2020.100934

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