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Multifunctional Protein Conjugates with Built-in Adjuvant (Adjuvant-Protein-Antigen) as Cancer Vaccines Boost Potent Immune Responses

Many cancer vaccines are not successful in clinical trials, mainly due to the challenges associated with breaking immune tolerance. Herein, we report a new strategy using an adjuvant-protein-antigen (three-in-one protein conjugates with built-in adjuvant) as an anticancer vaccine, in which both the...

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Detalles Bibliográficos
Autores principales: Du, Jing-Jing, Wang, Chang-Wei, Xu, Wen-Bo, Zhang, Lian, Tang, Yuan-Kai, Zhou, Shi-Hao, Gao, Xiao-Fei, Yang, Guang-Fu, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063246/
https://www.ncbi.nlm.nih.gov/pubmed/32146328
http://dx.doi.org/10.1016/j.isci.2020.100935