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Transcriptomic changes associated with PCK1 overexpression in hepatocellular carcinoma cells detected by RNA-seq

Phosphoenolpyruvate carboxykinase 1 (PCK1), a step limiting enzyme of gluconeogenesis, is downregulated in hepatocellular carcinoma (HCC). Overexpression of PCK1 has been shown to suppress hepatoma cell growth, but the underlying mechanism remains unclear. We used recombinant adenovirus overexpressi...

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Detalles Bibliográficos
Autores principales: Xiang, Jin, Zhang, Yuhong, Tuo, Lin, Liu, Rui, Gou, Dongmei, Liang, Li, Chen, Chang, Xia, Jie, Tang, Ni, Wang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063442/
https://www.ncbi.nlm.nih.gov/pubmed/32181286
http://dx.doi.org/10.1016/j.gendis.2019.04.004