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Fc-Linked IgG N-Glycosylation in FcγR Knock-Out Mice

Immunoglobulin G (IgG) is the most abundant immunoglobulin isotype in the blood and is involved in the pathogenesis and progression of various diseases. Glycosylation of the IgG fragment crystallizable (Fc) region is shown to vary in different physiological and pathological states. Fc N-glycan compo...

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Detalles Bibliográficos
Autores principales: Zaytseva, Olga O., Seeling, Michaela, Krištić, Jasminka, Lauc, Gordan, Pezer, Marija, Nimmerjahn, Falk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063467/
https://www.ncbi.nlm.nih.gov/pubmed/32195245
http://dx.doi.org/10.3389/fcell.2020.00067