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Metabolic and evolutionary responses of Clostridium thermocellum to genetic interventions aimed at improving ethanol production

BACKGROUND: Engineering efforts targeted at increasing ethanol by modifying the central fermentative metabolism of Clostridium thermocellum have been variably successful. Here, we aim to understand this variation by a multifaceted approach including genomic and transcriptomic analysis combined with...

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Detalles Bibliográficos
Autores principales: Holwerda, Evert K., Olson, Daniel G., Ruppertsberger, Natalie M., Stevenson, David M., Murphy, Sean J. L., Maloney, Marybeth I., Lanahan, Anthony A., Amador-Noguez, Daniel, Lynd, Lee R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063780/
https://www.ncbi.nlm.nih.gov/pubmed/32175007
http://dx.doi.org/10.1186/s13068-020-01680-5