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Blockage of O-linked GlcNAcylation induces AMPK-dependent autophagy in bladder cancer cells
BACKGROUND: High levels of the post-translational modification O-GlcNAcylation (O-GlcNAc) are found in multiple cancers, including bladder cancer. Autophagy, which can be induced by stress from post-translational modifications, plays a critical role in maintaining cellular homeostasis and regulating...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063793/ https://www.ncbi.nlm.nih.gov/pubmed/32174982 http://dx.doi.org/10.1186/s11658-020-00208-x |