Blockage of O-linked GlcNAcylation induces AMPK-dependent autophagy in bladder cancer cells

BACKGROUND: High levels of the post-translational modification O-GlcNAcylation (O-GlcNAc) are found in multiple cancers, including bladder cancer. Autophagy, which can be induced by stress from post-translational modifications, plays a critical role in maintaining cellular homeostasis and regulating...

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Detalles Bibliográficos
Autores principales: Jin, Lu, Yuan, Feng, Dai, Guangcheng, Yao, Qiu, Xiang, Han, Wang, Lixia, Xue, Boxin, Shan, Yuxi, Liu, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063793/
https://www.ncbi.nlm.nih.gov/pubmed/32174982
http://dx.doi.org/10.1186/s11658-020-00208-x

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