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Hemispheric asymmetry in the human brain and in Parkinson’s disease is linked to divergent epigenetic patterns in neurons

BACKGROUND: Hemispheric asymmetry in neuronal processes is a fundamental feature of the human brain and drives symptom lateralization in Parkinson’s disease (PD), but its molecular determinants are unknown. Here, we identify divergent epigenetic patterns involved in hemispheric asymmetry by profilin...

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Detalles Bibliográficos
Autores principales: Li, Peipei, Ensink, Elizabeth, Lang, Sean, Marshall, Lee, Schilthuis, Meghan, Lamp, Jared, Vega, Irving, Labrie, Viviane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063821/
https://www.ncbi.nlm.nih.gov/pubmed/32151270
http://dx.doi.org/10.1186/s13059-020-01960-1