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Genistein stimulates insulin sensitivity through gut microbiota reshaping and skeletal muscle AMPK activation in obese subjects

OBJECTIVE: Obesity is associated with metabolic abnormalities, including insulin resistance and dyslipidemias. Previous studies demonstrated that genistein intake modifies the gut microbiota in mice by selectively increasing Akkermansia muciniphila, leading to reduction of metabolic endotoxemia and...

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Detalles Bibliográficos
Autores principales: Guevara-Cruz, Martha, Godinez-Salas, Einar T, Sanchez-Tapia, Monica, Torres-Villalobos, Gonzalo, Pichardo-Ontiveros, Edgar, Guizar-Heredia, Rocio, Arteaga-Sanchez, Liliana, Gamba, Gerardo, Mojica-Espinosa, Raul, Schcolnik-Cabrera, Alejandro, Granados, Omar, López-Barradas, Adriana, Vargas-Castillo, Ariana, Torre-Villalvazo, Ivan, Noriega, Lilia G, Torres, Nimbe, Tovar, Armando R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064085/
https://www.ncbi.nlm.nih.gov/pubmed/32152146
http://dx.doi.org/10.1136/bmjdrc-2019-000948