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Rapamycin retards growth and causes marked alterations in the growth plate of young rats

Rapamycin is a potent immunosuppressant with antitumoral properties widely used in the field of renal transplantation. To test the hypothesis that the antiproliferative and antiangiogenic activity of rapamycin interferes with the normal structure and function of growth plate and impairs longitudinal...

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Detalles Bibliográficos
Autores principales: Alvarez-Garcia, Oscar, Carbajo-Pérez, Eduardo, Garcia, Enrique, Gil, Helena, Molinos, Ines, Rodriguez, Julian, Ordoñez, Flor A., Santos, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064183/
https://www.ncbi.nlm.nih.gov/pubmed/17370095
http://dx.doi.org/10.1007/s00467-007-0456-8