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Rapamycin retards growth and causes marked alterations in the growth plate of young rats
Rapamycin is a potent immunosuppressant with antitumoral properties widely used in the field of renal transplantation. To test the hypothesis that the antiproliferative and antiangiogenic activity of rapamycin interferes with the normal structure and function of growth plate and impairs longitudinal...
Autores principales: | Alvarez-Garcia, Oscar, Carbajo-Pérez, Eduardo, Garcia, Enrique, Gil, Helena, Molinos, Ines, Rodriguez, Julian, Ordoñez, Flor A., Santos, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064183/ https://www.ncbi.nlm.nih.gov/pubmed/17370095 http://dx.doi.org/10.1007/s00467-007-0456-8 |
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