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Gender differences in diet-induced steatotic disease in Cyp2b-null mice

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease; however, progression to nonalcoholic steatohepatitis (NASH) is associated with most adverse outcomes. CYP2B metabolizes multiple xeno- and endobiotics, and male Cyp2b-null mice are diet-induced obese (DIO) with increased NAFL...

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Detalles Bibliográficos
Autores principales: Heintz, Melissa M., McRee, Rebecca, Kumar, Ramiya, Baldwin, William S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064244/
https://www.ncbi.nlm.nih.gov/pubmed/32155178
http://dx.doi.org/10.1371/journal.pone.0229896