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TIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition

BACKGROUND: T-cell immunoglobulin and mucin domain-containing molecule-3 (TIM-3) was originally found to negatively regulate immune response and mediate immune escape in tumors. Subsequently, an increasing body of evidence has shown that TIM-3 exerts positive functions in the development and progres...

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Detalles Bibliográficos
Autores principales: Xiao, Yangyang, Qing, Jilin, Li, Baoxuan, Chen, Liuyan, Nong, Shengzhou, Yang, Wenhui, Tang, Xiaogang, Chen, Zhizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064287/
https://www.ncbi.nlm.nih.gov/pubmed/32184631
http://dx.doi.org/10.2147/OTT.S237222