Structural basis of transcription inhibition by the DNA mimic protein Ocr of bacteriophage T7

Bacteriophage T7 infects Escherichia coli and evades the host restriction/modification system. The Ocr protein of T7 was shown to exist as a dimer mimicking DNA and to bind to host restriction enzymes, thus preventing the degradation of the viral genome by the host. Here we report that Ocr can also...

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Detalles Bibliográficos
Autores principales: Ye, Fuzhou, Kotta-Loizou, Ioly, Jovanovic, Milija, Liu, Xiaojiao, Dryden, David TF, Buck, Martin, Zhang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064336/
https://www.ncbi.nlm.nih.gov/pubmed/32039758
http://dx.doi.org/10.7554/eLife.52125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064336/
https://www.ncbi.nlm.nih.gov/pubmed/32039758
http://dx.doi.org/10.7554/eLife.52125

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