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Structural basis of transcription inhibition by the DNA mimic protein Ocr of bacteriophage T7
Bacteriophage T7 infects Escherichia coli and evades the host restriction/modification system. The Ocr protein of T7 was shown to exist as a dimer mimicking DNA and to bind to host restriction enzymes, thus preventing the degradation of the viral genome by the host. Here we report that Ocr can also...
Autores principales: | Ye, Fuzhou, Kotta-Loizou, Ioly, Jovanovic, Milija, Liu, Xiaojiao, Dryden, David TF, Buck, Martin, Zhang, Xiaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064336/ https://www.ncbi.nlm.nih.gov/pubmed/32039758 http://dx.doi.org/10.7554/eLife.52125 |
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