A novel role for lipoxin A(4) in driving a lymph node–eye axis that controls autoimmunity to the neuroretina

The eicosanoid lipoxin A(4) (LXA(4)) has emerging roles in lymphocyte-driven diseases. We identified reduced LXA(4) levels in posterior segment uveitis patients and investigated the role of LXA(4) in the pathogenesis of experimental autoimmune uveitis (EAU). Immunization for EAU with a retinal self-...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Jessica, Mattapallil, Mary J, Horai, Reiko, Jittayasothorn, Yingyos, Modi, Arnav P, Sen, H Nida, Gronert, Karsten, Caspi, Rachel R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064344/
https://www.ncbi.nlm.nih.gov/pubmed/32118582
http://dx.doi.org/10.7554/eLife.51102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064344/
https://www.ncbi.nlm.nih.gov/pubmed/32118582
http://dx.doi.org/10.7554/eLife.51102

Ejemplares similares