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The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion

Protein secretion through type-three secretion systems (T3SS) is critical for motility and virulence of many bacteria. Proteins are transported through an export gate containing three proteins (FliPQR in flagella, SctRST in virulence systems). A fourth essential T3SS protein (FlhB/SctU) functions to...

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Detalles Bibliográficos
Autores principales: Kuhlen, Lucas, Johnson, Steven, Zeitler, Andreas, Bäurle, Sandra, Deme, Justin C., Caesar, Joseph J.  E., Debo, Rebecca, Fisher, Joseph, Wagner, Samuel, Lea, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064499/
https://www.ncbi.nlm.nih.gov/pubmed/32157081
http://dx.doi.org/10.1038/s41467-020-15071-9