Cargando…

The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion

Protein secretion through type-three secretion systems (T3SS) is critical for motility and virulence of many bacteria. Proteins are transported through an export gate containing three proteins (FliPQR in flagella, SctRST in virulence systems). A fourth essential T3SS protein (FlhB/SctU) functions to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kuhlen, Lucas, Johnson, Steven, Zeitler, Andreas, Bäurle, Sandra, Deme, Justin C., Caesar, Joseph J. E., Debo, Rebecca, Fisher, Joseph, Wagner, Samuel, Lea, Susan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064499/ https://www.ncbi.nlm.nih.gov/pubmed/32157081 http://dx.doi.org/10.1038/s41467-020-15071-9

Ejemplares similares

Cross-Complementation Study of the Flagellar Type III Export Apparatus Membrane Protein FlhB
por: Barker, Clive S., et al.
Publicado: (2012)

Targeting early proximal-rod component substrate FlgB to FlhB for flagellar-type III secretion in Salmonella
por: Qu, Daofeng, et al.
Publicado: (2022)

Weak Interactions between Salmonella enterica FlhB and Other Flagellar Export Apparatus Proteins Govern Type III Secretion Dynamics
por: McMurry, Jonathan L., et al.
Publicado: (2015)

Function of FlhB, a Membrane Protein Implicated in the Bacterial Flagellar Type III Secretion System
por: Meshcheryakov, Vladimir A., et al.
Publicado: (2013)

The Structure of an Injectisome Export Gate Demonstrates Conservation of Architecture in the Core Export Gate between Flagellar and Virulence Type III Secretion Systems
por: Johnson, Steven, et al.
Publicado: (2019)

A Proline-Rich Element in the Type III Secretion Protein FlhB Contributes to Flagellar Biogenesis in the Beta- and Gamma-Proteobacteria
por: Hook, John C., et al.
Publicado: (2020)

Structure of the Core of the Type Three Secretion System Export Apparatus
por: Kuhlen, Lucas, et al.
Publicado: (2018)

One-Step PCR Detection of Salmonella Pullorum/Gallinarum Using a Novel Target: The Flagellar Biosynthesis Gene flhB
por: Xiong, Dan, et al.
Publicado: (2016)

Nonameric structures of the cytoplasmic domain of FlhA and SctV in the context of the full-length protein
por: Kuhlen, Lucas, et al.
Publicado: (2021)

Structures of chaperone-substrate complexes docked onto the export gate in a type III secretion system
por: Xing, Qiong, et al.
Publicado: (2018)

Flagellar Basal Body Structural Proteins FlhB, FliM, and FliY Are Required for Flagellar-Associated Protein Expression in Listeria monocytogenes
por: Cheng, Changyong, et al.
Publicado: (2018)

The FlhA linker mediates flagellar protein export switching during flagellar assembly
por: Inoue, Yumi, et al.
Publicado: (2021)

Conserved GYXLI Motif of FlhA Is Involved in Dynamic Domain Motions of FlhA Required for Flagellar Protein Export
por: Minamino, Tohru, et al.
Publicado: (2022)

Direct interaction of a chaperone-bound type III secretion substrate with the export gate
por: Gilzer, Dominic, et al.
Publicado: (2022)

Genetic Characterization of Conserved Charged Residues in the Bacterial Flagellar Type III Export Protein FlhA
por: Hara, Noritaka, et al.
Publicado: (2011)

Insight into structural remodeling of the FlhA ring responsible for bacterial flagellar type III protein export
por: Terahara, Naoya, et al.
Publicado: (2018)

Interdependent Polar Localization of FlhF and FlhG and Their Importance for Flagellum Formation of Vibrio parahaemolyticus
por: Arroyo-Pérez, Erick Eligio, et al.
Publicado: (2021)

Switching off Bacterial Flagellar Biogenesis by YdiU-Mediated UMPylation of FlhDC
por: Ma, Yue, et al.
Publicado: (2022)

Three small partner proteins facilitate the type VII-dependent secretion export of an antibacterial nuclease
por: Yang, Yaping, et al.
Publicado: (2023)

GTP-Dependent FlhF Homodimer Supports Secretion of a Hemolysin in Bacillus cereus
por: Mazzantini, Diletta, et al.
Publicado: (2020)

The flexible linker of the secreted FliK ruler is required for export switching of the flagellar protein export apparatus
por: Kinoshita, Miki, et al.
Publicado: (2020)

The type III secretion chaperone SctY may shield the hydrophobic export gate-binding C-terminus of its substrate SctX
por: Gilzer, Dominic, et al.
Publicado: (2023)

Spontaneous mutations in the flhD operon generate motility heterogeneity in Escherichia coli biofilm
por: Horne, Shelley M., et al.
Publicado: (2016)

Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains structural coordination of secretion and rotation
por: Johnson, Steven, et al.
Publicado: (2020)

The extracellular gate shapes the energy profile of an ABC exporter
por: Hutter, Cedric A. J., et al.
Publicado: (2019)

“The structure of the Type III secretion system export gate with CdsO, an ATPase lever arm”
por: Jensen, Jaime L., et al.
Publicado: (2020)

FlhF Is Required for Swarming Motility and Full Pathogenicity of Bacillus cereus
por: Mazzantini, Diletta, et al.
Publicado: (2016)

HPLC-qTOF-MS/MS-Based Profiling of Flavan-3-ols and Dimeric Proanthocyanidins in Berries of Two Muscadine Grape Hybrids FLH 13-11 and FLH 17-66
por: Yuzuak, Seyit, et al.
Publicado: (2018)

The motility regulator flhDC drives intracellular accumulation and tumor colonization of Salmonella
por: Raman, Vishnu, et al.
Publicado: (2019)

OmpR controls Yersinia enterocolitica motility by positive regulation of flhDC expression
por: Raczkowska, Adrianna, et al.
Publicado: (2010)

Transcriptional organization, regulation and functional analysis of flhF and fleN in Pseudomonas putida
por: Navarrete, Blanca, et al.
Publicado: (2019)

Insights into the impact of flhF inactivation on Campylobacter jejuni colonization of chick and mice gut
por: Ren, Fangzhe, et al.
Publicado: (2018)

FlhF(T368A) modulates motility in the bacteriophage carrier state of Campylobacter jejuni
por: Liang, Lu, et al.
Publicado: (2018)

Analysis of the GTPase motif of FlhF in the control of the number and location of polar flagella in Vibrio alginolyticus
por: Kondo, Shota, et al.
Publicado: (2017)

Strain-dependent motility defects and suppression by a flhO mutation for B. subtilis bactofilins
por: Holtrup, Sven, et al.
Publicado: (2022)

Genomic SELEX Reveals Pervasive Role of the Flagella Master Regulator FlhDC in Carbon Metabolism
por: Takada, Hiraku, et al.
Publicado: (2023)

Antidurotaxis Droplet Motion onto Gradient Brush Substrates
por: Kajouri, Russell, et al.
Publicado: (2023)

Revealing the mechanisms of membrane protein export by virulence-associated bacterial secretion systems
por: Krampen, Lea, et al.
Publicado: (2018)

Architecture of the major component of the type III secretion system export apparatus
por: Abrusci, Patrizia, et al.
Publicado: (2012)

Crystals of SctV from different species reveal variable symmetry for the cytosolic domain of the type III secretion system export gate
por: Gilzer, Dominic, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4ldtg95s3v47he44v85m582qfl