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Post-translational Modifications of the Peptidyl-Prolyl Isomerase Pin1

The peptidyl-prolyl cis/trans isomerase (PPIase) Pin1 is a unique enzyme that only binds to Ser/Thr-Pro peptide motifs after phosphorylation and regulates the conformational changes of the bond. The Pin1-catalyzed isomerization upon phosphorylation can have profound effects on substrate biological f...

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Detalles Bibliográficos
Autores principales: Chen, Dongmei, Wang, Long, Lee, Tae Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064559/
https://www.ncbi.nlm.nih.gov/pubmed/32195254
http://dx.doi.org/10.3389/fcell.2020.00129