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Challenges and Perspectives in Chemical Synthesis of Highly Hydrophobic Peptides

Solid phase peptide synthesis (SPPS) provides the possibility to chemically synthesize peptides and proteins. Applying the method on hydrophilic structures is usually without major drawbacks but faces extreme complications when it comes to “difficult sequences.” These includes the vitally important,...

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Detalles Bibliográficos
Autores principales: Mueller, Lena K., Baumruck, Andreas C., Zhdanova, Hanna, Tietze, Alesia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064641/
https://www.ncbi.nlm.nih.gov/pubmed/32195241
http://dx.doi.org/10.3389/fbioe.2020.00162