Heterosubtypic Protection Induced by a Live Attenuated Influenza Virus Vaccine Expressing Galactose-α-1,3-Galactose Epitopes in Infected Cells

Anti-galactose-α-1,3-galactose (anti-α-Gal) antibody is naturally expressed at a high level in humans. It constitutes about 1% of immunoglobulins found in human blood. Here, we designed a live attenuated influenza virus vaccine that can generate α-Gal epitopes in infected cells in order to facilitat...

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Detalles Bibliográficos
Autores principales: Yan, Li-Meng, Lau, Sylvia P. N., Poh, Chek Meng, Chan, Vera S. F., Chan, Michael C. W., Peiris, Malik, Poon, Leo L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064743/
https://www.ncbi.nlm.nih.gov/pubmed/32127444
http://dx.doi.org/10.1128/mBio.00027-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064743/
https://www.ncbi.nlm.nih.gov/pubmed/32127444
http://dx.doi.org/10.1128/mBio.00027-20

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