New Host-Directed Therapeutics for the Treatment of Clostridioides difficile Infection

Frequent and excessive use of antibiotics primes patients to Clostridioides difficile infection (CDI), which leads to fatal pseudomembranous colitis, with limited treatment options. In earlier reports, we used a drug repurposing strategy and identified amoxapine (an antidepressant), doxapram (a brea...

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Detalles Bibliográficos
Autores principales: Andersson, Jourdan A., Peniche, Alex G., Galindo, Cristi L., Boonma, Prapaporn, Sha, Jian, Luna, Ruth Ann, Savidge, Tor C., Chopra, Ashok K., Dann, Sara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064747/
https://www.ncbi.nlm.nih.gov/pubmed/32156806
http://dx.doi.org/10.1128/mBio.00053-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064747/
https://www.ncbi.nlm.nih.gov/pubmed/32156806
http://dx.doi.org/10.1128/mBio.00053-20

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